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Regulatory intelligence
FDAsafety guidance72% confidence

FDA Alerts Health Care Providers to Cases of Neurologic Complications from General Anesthesia Linked to Genetic Variant in Patients of Maternal Venezuelan Ancestry

Source: FDA

Why This Matters

Why this matters: sets a safety guidance precedent in the same sub-indication (cardiology) as Anthos Therapeutics.

Regulatory Analysis

Food and Drug Administration (FDA) is investigating the safety of sevoflurane and other general anesthetics based on published scientific reports of unexpected catastrophic outcomes, including severe neurologic adverse outcomes and death, occurring in adult and pediatric patients.

Supporting Context

Therapeutic area
Cardiology · Atrial Fibrillation
Sub-indication
Hypertension

Related signal: Anthos and Novartis initiate LILAC-TIMI 76 trial for abelacimab in high-risk AF patients

Source

View source document

Related Signal

Open signal — Anthos and Novartis initiate LILAC-TIMI 76 trial for abelacimab in high-risk AF patients
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