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FDA

Regulatory intelligence
FDAapproval72% confidence

FDA approves zidesamtinib for ROS1-positive non-small cell lung cancer

Source: FDA

Why This Matters

Why this matters: sets a approval precedent in the same sub-indication (breast cancer) as AstraZeneca.

Regulatory Analysis

On July 22, 2026, the Food and Drug Administration approved zidesamtinib (Jideytro, Nuvalent, Inc.) for adults with locally advanced or metastatic ROS1-positive non-small cell lung cancer (NSCLC) who received at least one prior ROS1 tyrosine kinase inhibitor (TKI).

Supporting Context

Therapeutic area
Oncology · Breast Cancer
Sub-indication
Breast Cancer

Related signal: Datroway Approved in EU for Metastatic TNBC as First TROP2-Directed Therapy

Source

View source document

Related Signal

Open signal — Datroway Approved in EU for Metastatic TNBC as First TROP2-Directed Therapy
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